(1) A material that does not contain an infectious substance orthat is unlikely to cause disease in humans or animals. It is not an official legal edition of the CFR. 3.6.2.1 Definitions 3.6.2.2.2.1 Category A: An infectious substance which 3 For the purposes of these Regulations: is transported in a form that, when exposure to it occurs, is capable of causing permanent disability, life-threatening 3.6.2.1.1 Infectious substances are substances which or fatal disease in otherwise healthy humans or animals. Category A infectious substances must be packaged according to the following requirements, depending on the physical state and other characteristics of the material. Pre-labeled outer packaging and Category B Substance labels can be ordered from our Supply Storefront or purchased from multiple vendors. If dry ice is used, the outer packaging or overpack must permit the release of carbon dioxide gas and otherwise meet the provisions in 173.217. Infectious substances that come under Class 6 Infectious Substances (Division 6.2) are divided into 3 categories. Fire Protection Impairment and Fire Watch, Flu Planning Checklist For Event & Program Coordinators, Infectious Disease Preparedness for Event Planners, Mobile Vending and Food Truck Operations Requirements, Other Resources and Procedures for Safety, Biological Safety Manuals and Other Documents, Hazard Assessment and Signage Program (HASP), Dry Ice, Formaldehyde, Lithium Batteries, GMO's, Emergency Management and Business Continuity. Category A Infectious Substances Some shipped substances are classified as either Category A infectious substances or Category B biological substances. An infectious substance must be assigned to one of the following two packaging categories: Category B infectious substance transported for Research, Diagnosis, Investigation activities, Disease treatment or prevention, or biological product transported in a motor vehicle used exclusively to transport such materials. Category A which is capable of causing . The absorbent material must be sufficient to absorb the entire contents of all primary receptacles. Category B Infectious Substances . This document is available in the following developer friendly formats: Information and documentation can be found in our Do not step in any spill from the shipment (recommend shoe covers). Protective steps for personnel should include securing area to prevent spreading of material, also prevent inhalation, ingestion or contact. Overview of Dangerous Goods Shipping Category A Infectious Substances . Ice, dry ice, or other refrigerant must be placed around the secondary packagings or in an overpack with one or more complete packages marked in accordance with 178.503 of this subchapter. Clinical wastes containing Category A infectious substances must be assigned to UN 2814 or UN 2900, as appropriate. Imagine a culture for strep throat where it is in a vial trying to be reproduced. Infectious specimens and materials with pathogens included in Category A of the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR) must be transported . Title 49 was last amended 11/03/2022. Primary receptacles must be made of glass, metal, or plastic. Indicative examples of substances that meet these criteria are given in Table 3.6.D.' ( IATA Dangerous Goods Regulation, 3.6.2.2.2.1) 'An infectious substance which is transported in a form that, when exposure to it occurs, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. Patient Specimens: Tissue, blood, excreta, body parts, and other types of specimens collected from the body of a human or animal. Cultures . Classification must be based on the known medical history or symptoms of the source patient or animal, endemic local conditions, or professional judgment concerning the individual circumstances of the source human or animal. When the Infectious Substances to be transported are unknown, but suspected of meeting the criteria of Category A, and assigned to UN 2814 or UN 2900, the words "Suspected Category A Infectious Substance" must be shown in parenthesis following the proper shipping name on the Shipper's Declaration of Dangerous (You can unsubscribe anytime), Learn More About USDOT/HazMat Transportation, The Requirements of 40 CFR 262.265 Emergency Procedures of Contingency Plan for Large Quantity Generator of Hazardous Waste, Proteinaceous infectious particle (prion), Burkholderia malleiPseudomonas malleiGlanders (cultures only), Burkholderia pseudomalleiPseudomonas pseudomallei (cultures only), Chlamydia psittaciavian strains (cultures only), Eastern equine encephalitis virus (cultures only), Escherichia coli, verotoxigenic (cultures only), Hantaviruses causing hemorrhagic fever with renal syndrome, Human immunodeficiency virus (cultures only), Highly pathogenic avian influenza virus (cultures only), Japanese Encephalitis virus (cultures only), Mycobacterium tuberculosis (cultures only), Rabies and other lyssaviruses (cultures only), Russian spring-summer encephalitis virus (cultures only), Shigella dysenteriae type I (cultures only), Tick-borne encephalitis virus (cultures only), Venezuelan equine encephalitis virus (cultures only), Vesicular stomatitis virus (cultures only), African swine fever virus (cultures only), Avian paramyxovirus Type 1Velogenic Newcastle disease virus (cultures only), Classical swine fever virus (cultures only), Foot and mouth disease virus (cultures only), Mycoplasma mycoidesContagious bovine pleuropneumonia (cultures only), Peste des petits ruminants virus (cultures only), Swine vesicular disease virus (cultures only). In addition to Category B infectious substances, cultures . This can be human, animal, bacterial, viral, or fungal material transported for research, diagnosis, disease, or treatment. Shipping Biological Materials - Environment, Health and Safety (Air shipments). Interior supports must be provided to secure the secondary packagings in the original position after the ice or dry ice has dissipated. The secondary container inside is a plastic seal bag or a screw-top cylinder. Indicative Examples of Infectious Substances Included in Category A in Any Form Unless Otherwise Indicated ( iata dangerous Goods Regulations ). (a) Category A infectious substances packaging. What is an Infectious Substance, Category B (also known as Biological Substance, Category B)? Infectious Substance Special Permits; COVID-19 Information; Planning Guidance for Handling Category A Solid Waste. While there are exceptions from full regulation for certain Category B Infectious Substances at 173.134(b), it is unlikely there will be any exception from full regulation for a Category A Infectious Substance. Category A substances are infectious substances which are transported in a form that, when exposure to them occurs, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. Category A infectious substances -- including the Ebola virus -- may only be transported in two scenarios; in full compliance with classification and packaging requirements of the HMR; or under the terms of a special permit. Category A - Infectious substance 6.2 Definition - A pathogen (infectious substance) capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. packaging of infectious substances must have received training appropriate to the level of the task. Most hospital clinical labs or public health lab could do so, especially if they have Bio-safety level 2 capability. An exposure occurs when an infectious substance is released outside of its protective packaging, resulting in physical contact with humans or animals. Work with these substances usually What are some of the limitations for shipping infectious substances? Display other package marks as required by the HMR. Biological Substance, Category A: an infectious substance which in a form that, when exposure to it occurs, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. (c) Live animals may not be used to transport infectious substances unless such substances cannot be sent by any other means. Infectious This Category A, UN 2900 & UN 2814, online training covers all aspects of Class 6.2 Infectious Substances transportation regulations, needed to comply with shipping regulations and IATA. Find the Right Hazmat Box to Fit Your Needs Comments or questions about document content can not be answered by OFR staff. That list, however is not exhaustive. 1.5 cups of bleach to 1 gallon of water). Category B Packaging Markings Place the markings for a Category B infectious substance on the outer packaging. Category A packaging uses a three-layer system with multiple built-in failsafes to maximize safety without compromising performance. formatting. This is a square cardboard box with a styrofoam insert. This is a square cardboard box with a styrofoam insert. A pathogen is a microorganism or other agent that can cause disease in humans or animals. If there is obvious broken glass or other sharp items, it should go in a rigid leak-proof container, and then can go into the plastic bags. A packaging for a Division 6.2 material that is a Category A infectious substance must meet the test standards of 178.609 of this subchapter and must be marked in conformance with 178.503(f) of this subchapter. Authorized packaging and the packing instructions for a Category A Infectious Substance are found at 173.196 and will include the following: And, of course, all personnel with a direct effect on the safe transportation of this HazMat (i.e., pack, label, mark, load or unload vehicle, operate motor vehicle, prepare / review / sign the shipping paper, or directly supervise any person performing any of the preceding must receive initial and recurrent HazMat Employee Training. This is an automated process for Infectious substances that would be shipped in this . For clean-up of spills, wear a mask (recommend NIOSH approved N95 particulate respiratory type), eye protection (recommend safety goggles), gloves (recommend nitrile), and protective gown (basically something to put over street clothes to protect them from contamination). For the best experience on our site, be sure to turn on Javascript in your browser. The Electronic Code of Federal Regulations (eCFR) is a continuously updated online version of the CFR. Place all items and the paper towels in a double set of leak-proof plastic bags, preferably with a biohazard label on them. An animal containing or contaminated with an infectious substance must be transported under terms and conditions approved by the Associate Administrator for Hazardous Materials Safety. 3.6 Please do not provide confidential Cover the spill with paper toweling, and generously soak the toweling with the disinfectant. In all cases there is always enough absorbent material in the secondary container, capable of absorbing all liquid. The transportation of infectious substances is divided into the following categories: Category A: an infectious substance which is carried in a form that, when exposure to it occurs, is capable of causing permanent disability, life threatening or fatal disease in otherwise healthy humans or animals. UN 2814, Infectious Substance, Affecting Humans, Category A, UN 2900, Infectious Substance, Affecting Animals, Category A. This course is also for those shipping Biological Substances Category B with Dry Ice or Nitrogen. These shippers are developed in accordance to the regulations set forth by the USDOT, Transport Canada, ICAO and IATA. Medical Waste: Waste material produced by medical facilities such as used syringes, gloves, gowns, etc. Subscribe to: Changes in Title 49 :: Subtitle B :: Chapter I :: Subchapter C :: Part 173 :: Subpart E :: Section 173.196. We recommend you directly contact the agency responsible for the content in question. Dry Ice (UN1845) 49 CFR 173.217. category A infectious substance An infectious substance which, when exposure to it occurs, is capable of causing permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals. The VOLO product line uses unique water-based brick cassettes and an innovative graphite-infused polystyrene insulated chest, Neopor. Examples of Infectious Substances and Biological Substances (Category A and B) Page 2 Last Updated: 07/17/2019 Hantavirus causing haemorrhagic fever with renal syndrome X Hendra virus X Hepatitis B virus cultures X (Always) Other materials containing the Hepatitis B virus X Herpes B virus cultures X Microorganism Category A Category B Human . Cat A Waste Planning Guidance_Final_2022_06.pdf (2.79 MB) DOT is committed to ensuring that information is available in appropriate alternative formats to meet the requirements of persons who have a disability. All shipments of Infectious Substance, Affecting Humans or Animals, Category A - are shipped according to Packing Instruction 620. The information in this booklet is current as of July, 2012 Classification of Division 6.2 Infectious Substances Category A An infectious substance transported in a form capable of causing permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals when exposure occurs. (5) An itemized list of contents enclosed between the secondary packaging and the outer packaging. result, it may not include the most recent changes applied to the CFR. View the most recent official publication: These links go to the official, published CFR, which is updated annually. ( 1) Infectious substances shipped at ambient temperatures or higher. Primary receptacles must be made of glass, metal, or plastic. A separate drafting site The most common examples are in appendix A at the end of this document copied from the training manual. The primary receptacle and the secondary packaging must maintain their integrity at the temperature of the refrigerant used, as well as the temperatures and pressures of transport by aircraft to which they could be subjected if refrigeration were lost. D Get the latest updates, news, and regulations for HazMat Transport and Waste Management. Category A Infectious Substances are infectious substances in a form that, when exposure to it occurs, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. If elements in these checklists are missing for any package containing a Category A specimen, the package is improperly prepared according to WAPHL requirements and may be in violation of federal regulations. Nomenclature changes to part 173 appear at 70 FR 56098, Sept. 23, 2005. These facilities also have set-ups for disposing of bio-hazardous waste. Example: Yes, I would like to receive emails from Daniels Training Services. Use the navigation links in the gray bar above to view the table of contents that this content belongs to. Category A: An infectious substance transported in a form capable of causing permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals when exposure occurs. High-priority agents include organisms that pose a risk to national security because they Included in the twenty hazard classes and divisions identified in the HMR at 49 CFR 173.134 is Division 6.2 Infections Substance; Divisions 6.2 is further broken down into Category A and Category B. category B infectious substance: An infectious substance that does not meet the criteria for Category A ("dangerous pathogen"), which is defined as an infectious substance which, when exposure to it occurs, can cause permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals. If you have questions for the Agency that issued the current document please contact the agency directly. Indicative Examples of Infectious Substances Included in Category A in Any Form Unless Otherwise Indicated (source: IATA Dangerous Goods Regulations, 56th EDITION, 1 JANUARY 2015) Infectious substance affecting humans Bacillus anthracis (cultures only) Brucella abortus (cultures only) Brucella melitensis (cultures only) Brucella suis (cultures only) Burkholderia mallei-Pseudomonas mallei . (2) Non-infectious biological materials from humans, animals, or plants. If you have a disability and are having trouble accessing information on this website or need materials in an alternate format, contact web-accessibility@cornell.edu for assistance. Thus, when shipping substances such as medical specimens that may contain infectious substances, its critical to observe infectious substances regulations to the letter. Examples of pathogens include bacteria, viruses, fungi, and other infectious agents. Category A Infectious Substances are infectious substances in a form that, when exposure to it occurs, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. 395 Pine Tree Road, Suite 210 Category B Infectious Substances. Category A Definition The U.S. public health system and primary healthcare providers must be prepared to address various biological agents, including pathogens that are rarely seen in the United States. All shipments of Infectious Substance, Affecting Humans or Animals, Category A - are shipped according to Packing Instruction 620. (3) A rigid outer packaging of adequate strength for its capacity, mass and intended use; including, drums (1A1, 1A2, 1B1, 1B2, 1N1, 1N2, 1H1, 1H2, 1D, 1G); boxes (4A, 4B, 4N, 4C1, 4C2, 4D, 4F, 4G, 4H1, 4H2); or jerricans (3A1, 3A2, 3B1, 3B2, 3H1, 3H2). Contact EHS, (831) 459-2553. This contact form is only for website help or website suggestions. All packages containing infectious substances must be marked durably and legibly on the outside of the package with the Category A infectious substances must be packaged according to the following requirements, depending on the physical state and other characteristics of the material. (2) Infectious substances shipped refrigerated or frozen (ice, pre-frozen packs, dry ice). The certified containers that are used to transport Category A specimens are more expensive as well. 173-224, 55 FR 52643, Dec. 21, 1990, unless otherwise noted. Indicative List of Category A Substances UN Number and Proper Shipping Name Micro-organism UN 2814 Infectious substance, affecting humans Bacillus anthracis (cultures only) Brucella abortus (cultures only) Brucella melitensis (cultures only) Brucella suis (cultures only) Burkholderia mallei - Pseudomonas mallei - Glanders (cultures only) "An infectious substance which does not meet the criteria for inclusion in Category A. A dead rat, shipped to a laboratory to test for potential Yersinia pestis infection, is classified as: Category B Infectious substance. An exposure occurs when an infectious substance is released outside of its protective packaging, resulting in physical contact with humans or animals. The outer packaging must measure not less than 100 mm (3.9 inches) at its smallest overall external dimension. - Other Regulations Relating to Transportation, - Pipeline and Hazardous Materials Safety Administration, Department of Transportation, - Shippers - General Requirements for Shipments and Packagings, - Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7, https://www.ecfr.gov/current/title-49/subtitle-B/chapter-I/subchapter-C/part-173/subpart-E/section-173.196. This content is from the eCFR and is authoritative but unofficial. These shipments must follow Packing Instructions 620. Illustrative examples of substances that meet these criteria are given in class 3.6. The use of safety relief valves, check valves, frangible discs, or similar devices in the vent lines is prohibited. The Code of Federal Regulations (CFR) is the official legal print publication containing the codification of the general and permanent rules published in the Federal Register by the departments and agencies of the Federal Government. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. 3.6.2.2.2.1 Category A: An infectious substance which is transported in a form and transforming it, touching or interacting with him, is capable of causing permanent disability, life-threatening or fatal disease in otherwise healthy humans or animals. Display the UN Standard mark on the outer packaging per 178.503(f). A Category A infectious substance is one in a form capable of causing permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals when exposure to it occurs. or existing codification. Refrigerated liquid nitrogen packagings must be metal vacuum insulated vessels or flasks vented to the atmosphere to prevent any increase in pressure within the packaging. UN2814 Brucella abortus (cultures only). No changes found for this content after 1/03/2017. Category A Infectious Substances (UN2814) 49 CFR 173.196. Get all the latest information on Events, Sales and Offers. A Category B substance is an infectious substance which does not meet the criteria for inclusion in Category A. An infectious substance which does not meet the criteria for inclusion in Category A. Category A packaging uses a three-layer system with multiple built-in failsafes to maximize safety without compromising performance. Category A Infectious Substance Packaging Category A infectious substances must be shipped in a specific type of packaging that's designed to contain the infectious agents and prevent them from spreading. Update to identify that the mark in the diamond applied to packages containing biological substances, Category B (UN 3373) and genetically . in Category A and assignment to UN 2814 or UN 2900, the words "suspected category A infectious substance" shall be shown, in parentheses, following the proper shipping name on the transport document but not on the outer packaging. Examples of pathogens include bacteria, viruses, fungi, and other infectious agents. learn more about the process here. Enhanced content is provided to the user to provide additional context. Category A infectious substances must be shipped in a specific type of packaging that's designed to contain the infectious agents and prevent them from spreading.